| dc.contributor.advisor |
Klásek, Antonín
|
|
| dc.contributor.author |
Křemenová, Hana
|
|
| dc.date.accessioned |
2016-11-28T11:42:55Z |
|
| dc.date.available |
2016-11-28T11:42:55Z |
|
| dc.date.issued |
2016-01-15 |
|
| dc.identifier |
Elektronický archiv Knihovny UTB |
|
| dc.identifier.uri |
http://hdl.handle.net/10563/38022
|
|
| dc.description.abstract |
Diplomová práce se zabývá studiem reakcí derivátů 3-chlorchinolin-2,4(1H,3H)-di-onů s ethanolaminem v N,N'-dimethylformamidu, při nichž byly úspěšně získány předpo-kládané produkty 3-(hydroxyethylamino)chinolin-2,4(1H,3H)-diony. Ty byly následně po-drobeny dalšímu zkoumání. Reakcemi s kyanatanem draselným byly získávány produkty v závislosti na substituci v polohách 1 a 3 na chinolinovém skeletu, konkrétně 2,6-dihydroimi-dazo[1,5-c]-chinazolin-3,5-dion, 3-(3'-hydroxyethylureido)-2-oxo-2,3-dihydro-indoly a 3-hydroxyethylspiro[imidazolidin-5,3´-indol]-2,2´-diony. Při reakci s trifosgenem byla snaha získat novou sloučeninu 3-(2-oxooxazolidin-3-yl)chinolin-2,4(1H,3H)-dionu, která se podařila izolovat z jedné vyzkoušené reakce. |
|
| dc.format |
68 s. |
|
| dc.language.iso |
cs |
|
| dc.publisher |
Univerzita Tomáše Bati ve Zlíně |
|
| dc.rights |
Bez omezení |
|
| dc.subject |
Nukleofilní substituce
|
cs |
| dc.subject |
3-chlorchinolin
|
cs |
| dc.subject |
1H
|
cs |
| dc.subject |
3H
|
cs |
| dc.subject |
-2
|
cs |
| dc.subject |
4-dion
|
cs |
| dc.subject |
ethanolamin
|
cs |
| dc.subject |
3-
|
cs |
| dc.subject |
hydroxyethylamino
|
cs |
| dc.subject |
-1H
|
cs |
| dc.subject |
3H-chinolin-2
|
cs |
| dc.subject |
4-dion
|
cs |
| dc.subject |
kyanatan draselný
|
cs |
| dc.subject |
trifosgen
|
cs |
| dc.subject |
Nucleophilic substitution of 3-chloroquinoline
|
en |
| dc.subject |
1H
|
en |
| dc.subject |
3H
|
en |
| dc.subject |
2
|
en |
| dc.subject |
4-dione
|
en |
| dc.subject |
ethanolamine
|
en |
| dc.subject |
3-
|
en |
| dc.subject |
hydroxyethylamino
|
en |
| dc.subject |
-1H
|
en |
| dc.subject |
3H-quinoline-2
|
en |
| dc.subject |
4-dione
|
en |
| dc.subject |
potassium cyanate
|
en |
| dc.subject |
triphosgene
|
en |
| dc.title |
Reakce 3-chlorchinolin-2,4-dionů s aminoalkoholy |
|
| dc.title.alternative |
Reactions of 3-Chloroquinoline-2,4-diones with Aminoalcohols |
|
| dc.type |
diplomová práce |
cs |
| dc.contributor.referee |
Kafka, Stanislav |
|
| dc.date.accepted |
2016-06-08 |
|
| dc.description.abstract-translated |
This master thesis studies the reactions of derivatives of 3-chloroquinoline-2,4(1H, 3H)-diones with ethanolamine in N,N'-dimethylformamide, in which the assumed products of 3-(hydroxyethylamino)quinoline-2,4(1H,3H)-diones have been successfully obtained. They were subsequently subjected to a series of reactions. During the reactions with potas-sium cyanate were obtained products depending on the substitution at positions 1 and 3 on the quinoline skeleton, namely 2,6-dihydroimidazo[1,5-c]-quinazoline-3,5-dione, 3-(3'-hyd-roxyethylureido)-2-oxo-2,3-dihydro-indole and 3-hydroxyethylspiro[imidazolidine-5,3'-in-dol]-2,2'-dione. In the reaction with triphosgene was an effort to obtain the novel compound 3-(2-oxo-oxazolidin-3-yl)-quinoline-2,4(1H,3H)-dione, which was successful isolate from the one tested reaction. |
|
| dc.description.department |
Ústav chemie |
|
| dc.thesis.degree-discipline |
Chemie potravin a bioaktivních látek |
cs |
| dc.thesis.degree-discipline |
Food Chemistry and Chemistry of Bioactive Substances |
en |
| dc.thesis.degree-grantor |
Univerzita Tomáše Bati ve Zlíně. Fakulta technologická |
cs |
| dc.thesis.degree-grantor |
Tomas Bata University in Zlín. Faculty of Technology |
en |
| dc.thesis.degree-name |
Ing. |
|
| dc.thesis.degree-program |
Chemie a technologie potravin |
cs |
| dc.thesis.degree-program |
Chemistry and Food Technologies |
en |
| dc.identifier.stag |
42881
|
|
| utb.result.grade |
A |
|
| dc.date.submitted |
2016-05-13 |
|
